BCL3 Antikörper (AA 118-366)

Produktnummer ABIN7870262

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch BCL3 in WB, ELISA, IF und FACS. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für BCL3 Antikörper (AA 118-366) (ABIN7870262)

Target: BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BCL3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Produktdetails anti-BCL3 Antikörper

Bindungsspezifität: AA 118-366

Verwendungszweck: B-cell lymphoma 3 Antibody / BCL3

Aufreinigung: Antigen affinity purified

Immunogen: An E.coli-derived human recombinant protein (amino acids E118-A366) was used as the immunogen for the B-cell lymphoma 3 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the B-cell lymphoma 3 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the B-cell lymphoma 3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu BCL3

Target: BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

Andere Bezeichnung: B-cell lymphoma 3

Hintergrund: B-cell lymphoma 3-encoded protein is a protein that in humans is encoded by the BCL3 gene. This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B.

UniProt: P20749

Pathways: NF-kappaB Signalweg, Maintenance of Protein Location, Protein targeting to Nucleus