PDK1 Antikörper (AA 114-436)

Produktnummer ABIN7870193

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PDK1 in WB, FACS und ELISA. Es zeigt Reaktivität gegenüber Proben von Human, Ratte und Maus.

Kurzübersicht für PDK1 Antikörper (AA 114-436) (ABIN7870193)

Target: PDK1 (Pyruvate Dehydrogenase Kinase 1 (PDK1))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), ELISA

Produktdetails anti-PDK1 Antikörper

Bindungsspezifität: AA 114-436

Verwendungszweck: Pyruvate dehydrogenase kinase 1 Antibody / PDK1

Aufreinigung: Antigen affinity purified

Immunogen: An E.coli-derived human recombinant protein (amino acids Y114-A436) was used as the immunogen for the Pyruvate dehydrogenase kinase 1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Pyruvate dehydrogenase kinase 1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Pyruvate dehydrogenase kinase 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu PDK1

Target: PDK1 (Pyruvate Dehydrogenase Kinase 1 (PDK1))

Andere Bezeichnung: Pyruvate dehydrogenase kinase 1

Hintergrund: Pyruvate dehydrogenase lipoamide kinase isozyme 1, mitochondrial is an enzyme that in humans is encoded by the PDK1 gene. Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene.

UniProt: Q15118

Pathways: PI3K-Akt Signalweg, RTK Signalweg, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Warburg Effekt