Rekombinanter Calnexin Antikörper (N-Term)

Produktnummer ABIN7869160

Der Kaninchen Monoklonal anti-Calnexin Antikörper (Klon CANX-9147R) (ABIN7869160) detektiert spezifisch Calnexin in WB, ELISA und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Rekombinanter Calnexin Antikörper (N-Term) (ABIN7869160)

Target: Calnexin (CANX)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Calnexin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: CANX-9147R

Produktdetails anti-Calnexin Antikörper

Bindungsspezifität: AA 1-300, N-Term

Verwendungszweck: Recombinant Calnexin Antibody

Aufreinigung: Protein A/G affinity

Immunogen: A recombinant N-terminal region fragment of human Calnexin protein (within amino acids 1-300) was used as the immunogen for the recombinant Calnexin antibody.

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the recombinant Calnexin antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the recombinant Calnexin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu Calnexin

Target: Calnexin (CANX)

Andere Bezeichnung: Calnexin

Hintergrund: It recognizes a protein of 90 kDa, which is identified as Calnexin. Secretory and transmembrane proteins are synthesized on polysomes and translocate into the endoplasmic reticulum (ER) where they are often modified by the formation of disulfide bonds, amino-linked glycosylation and folding. To help proteins fold properly, the ER contains a pool of molecular chaperones including calnexin. It is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation.

UniProt: P27824

Pathways: MAPK Signalweg, Thyroid Hormone Synthesis