PLK1 Antikörper (AA 1-200)

Produktnummer ABIN7868708

Dieser Maus Monoklonal Antikörper detektiert spezifisch PLK1 in ELISA und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für PLK1 Antikörper (AA 1-200) (ABIN7868708)

Target: PLK1 (Polo-Like Kinase 1 (PLK1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PLK1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse: Carrier-free

Klon: PLK1-7122

Produktdetails anti-PLK1 Antikörper

Bindungsspezifität: AA 1-200

Verwendungszweck: Polo like kinase 1 Antibody / PLK1 (azide and preservative free)

Aufreinigung: Protein A/G affinity

Immunogen: A recombinant fragment of human protein (within amino acids 1-200) was used as the immunogen for the Polo like kinase 1 antibody.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Polo like kinase 1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the Polo like kinase 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu PLK1

Target: PLK1 (Polo-Like Kinase 1 (PLK1))

Andere Bezeichnung: Polo like kinase 1

Hintergrund: Plk (for polo-like kinase) encodes a serine/threonine kinase that is closely related to polo and CDC5, genes that are required for passage through mitosis in Drosophila and Saccharomyces, respectively. Polo and CDC5 both code for proteins that are involved in regulating the function of the mitotic spindle. Plk protein accumulates in the cell during the S and G2 phases of the cell cycle, Plk protein content and catalytic activity peak at the onset of mitosis, followed by a rapid reduction after mitosis. Plk expression is detectable in mitotically active tissues such as colon and placenta, as well as in tumors of various origins. It has also been suggested that Plk may serve as a marker of cell proliferation.

UniProt: P53350

Pathways: Zellzyklus, M Phase