PLK1 Antikörper (AA 304-603)
Kurzübersicht für PLK1 Antikörper (AA 304-603) (ABIN3023352)
Target
Alle PLK1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 304-603
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Sequenz
- FFTSGYIPAR LPITCLTIPP RFSIAPSSLD PSNRKPLTVL NKGLENPLPE RPREKEEPVV RETGEVVDCH LSDMLQQLHS VNASKPSERG LVRQEEAEDP ACIPIFWVSK WVDYSDKYGL GYQLCDNSVG VLFNDSTRLI LYNDGDSLQY IERDGTESYL TVSSHPNSLM KKITLLKYFR NYMSEHLLKA GANITPREGD ELARLPYLRT WFRTRSAIIL HLSNGSVQIN FFQDHTKLIL CPLMAAVTYI DEKRDFRTYR LSLLEEYGCC KELASRLRYA RTMVDKLLSS RSASNRLKAS
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 304-603 of human PLK1 (NP_005021.2).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid freeze / thaw cycles
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- PLK1 (Polo-Like Kinase 1 (PLK1))
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Andere Bezeichnung
- PLK1
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Hintergrund
- The Ser/Thr protein kinase encoded by this gene belongs to the CDC5/Polo subfamily. It is highly expressed during mitosis and elevated levels are found in many different types of cancer. Depletion of this protein in cancer cells dramatically inhibited cell proliferation and induced apoptosis, hence, it is a target for cancer therapy.,PLK1,PLK,STPK13,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,Kinase,Serine/threonine kinases,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,G2/M DNA Damage Checkpoint,PLK1
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Molekulargewicht
- 68 kDa
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Gen-ID
- 5347
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UniProt
- P53350
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Pathways
- Zellzyklus, M Phase
Target
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