Rekombinanter Stathmin 1 Antikörper (AA 1-148)
Kurzübersicht für Rekombinanter Stathmin 1 Antikörper (AA 1-148) (ABIN7868180)
Target
Alle Stathmin 1 (STMN1) Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 1-148
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Verwendungszweck
- Recombinant STMN1 Antibody / Stathmin 1
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Aufreinigung
- Protein A/G affinity
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Immunogen
- A recombinant fragment (within amino acids 1-148) of human STMN1 protein was used as the immunogen for the recombinant STMN1 antibody.
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Isotyp
- IgG2b, kappa
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Applikationshinweise
- Optimal dilution of the recombinant STMN1 antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.2 mg/mL
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Buffer
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the recombinant STMN1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Stathmin 1 (STMN1)
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Andere Bezeichnung
- STMN1
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Hintergrund
- Stathmin 1 (Oncoprotein 18, STM1, prosolin or metablastin) is a conserved, Tubulin-associated, intracellular phosphoprotein. Many different phosphorylated forms of the protein are observed, and it is expressed as two different isoforms. Stathmin 1 is considered a critical regulator of microtubulin dynamics and is downregulated by p53. It serves as a transducing protein, via phophorylation, for a variety of cell signaling pathways and is involved in both mitosis and differentiation. It is present in many cancers, including breast carcinomas, and is highly expressed in acute leukemias of different subtypes.
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UniProt
- P16949
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Pathways
- MAPK Signalweg, Microtubule Dynamics
Target
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