AMACR Antikörper

Produktnummer ABIN7865557

Der Maus Monoklonal anti-AMACR Antikörper (Klon IHC504) (ABIN7865557) detektiert spezifisch AMACR in IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für AMACR Antikörper (ABIN7865557)

Target: AMACR (alpha-Methylacyl-CoA Racemase (AMACR))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser AMACR Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: IHC504

Produktdetails anti-AMACR Antikörper

Verwendungszweck: anti-p504s mouse monoclonal, IHC504, purified

Aufreinigung: affinity chromatography

Immunogen: Recombinant Human p504s

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optional[ICC/IF_dilution]: 1:50-1:200 (microwave treatment recommended)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Tris pH 7.3-7.7 with 1 % BSA and 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: store at 2 - 8 °C

Details zu AMACR

Target: AMACR (alpha-Methylacyl-CoA Racemase (AMACR))

Andere Bezeichnung: p504s

Hintergrund: P504s, also known as α-Methylacyl Coenzyme A Racemase (AMACR), is an enzyme localized in the peroxisome and mitochondria that functions in β-oxidation of branched chain fatty acids, as well as bile synthesis. AMACR has been clinically indicated as a tissue biomarker for prostate cancer and colorectal cancer, as well as high-grade prostatic intraepithelial neoplasia, a precursor lesion of prostate cancer. p504s overexpression has also been detected in a number of other cancers including ovarian, breast, bladder, lung, and renal cell carcinomas, lymphoma, and melanoma.

Pathways: Monocarboxylic Acid Catabolic Process