Rekombinanter Calnexin Antikörper (N-Term)

Produktnummer ABIN7860803

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch Calnexin in WB, IHC und ELISA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Rekombinanter Calnexin Antikörper (N-Term) (ABIN7860803)

Target: Calnexin (CANX)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Calnexin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Klon: CANX-9147R

Produktdetails anti-Calnexin Antikörper

Bindungsspezifität: AA 1-300, N-Term

Verwendungszweck: Recombinant Calnexin (Endoplasmic Reticulum Marker) Antibody

Spezifität: It recognizes a protein of 90 kDa, which is identified as Calnexin. Secretory and transmembrane proteins are synthesized on polysomes and translocate into the endoplasmic reticulum (ER) where they are often modified by the formation of disulfide bonds, amino-linked glycosylation and folding. To help proteins fold properly, the ER contains a pool of molecular chaperones including calnexin. It is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant N-terminal fragment of human Calnexin protein (around aa 1-300) (exact sequence is proprietary)

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Details zu Calnexin

Target: Calnexin (CANX)

Andere Bezeichnung: Calnexin

Hintergrund:

Calnexin, CANX, CNX, IP90, Major histocompatibility complex class I antigen-binding protein p88, P90

HeLa|MCF-7 or U2OS cells. Kidney or small intestine. Brain, Heart, Intestine, Kidney, Liver, Lung, Pancreas, Skin, Skeletal muscle and Stomach

Molekulargewicht: 90kDa

Gen-ID: 821, 567968

UniProt: P27824

Pathways: MAPK Signalweg, Thyroid Hormone Synthesis