PLK1 Antikörper (AA 1-200)

Produktnummer ABIN7864402

Der Maus Monoklonal anti-PLK1 Antikörper wird verwendet zum Nachweis von PLK1 in Proben von Human. Er wurde validiert für ELISA und IHC.

Kurzübersicht für PLK1 Antikörper (AA 1-200) (ABIN7864402)

Target: PLK1 (Polo-Like Kinase 1 (PLK1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PLK1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Klon: PLK1-7122

Produktdetails anti-PLK1 Antikörper

Bindungsspezifität: AA 1-200

Verwendungszweck: PLK1 Antibody

Spezifität: Plk (for polo-like kinase) encodes a serine/threonine kinase that is closely related to polo and CDC5, genes that are required for passage through mitosis in Drosophila and Saccharomyces, respectively. Polo and CDC5 both code for proteins that are involved in regulating the function of the mitotic spindle. Plk protein accumulates in the cell during the S and G2 phases of the cell cycle, Plk protein content and catalytic activity peak at the onset of mitosis, followed by a rapid reduction after mitosis. Plk expression is detectable in mitotically active tissues such as colon and placenta, as well as in tumors of various origins. It has also been suggested that Plk may serve as a marker of cell proliferation.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment of human PLK1 protein (around aa 1-200) (exact sequence is proprietary)

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Details zu PLK1

Target: PLK1 (Polo-Like Kinase 1 (PLK1))

Andere Bezeichnung: PLK1

Hintergrund:

Cell cycle regulated protein kinase, Polo like kinase 1, Serine/threonine protein kinase 13, Serine/threonine protein kinase PLK1, STPK13

Human tonsil|spleen or thymus.

Molekulargewicht: 66kDa

Gen-ID: 5347, 592049

UniProt: P53350

Pathways: Zellzyklus, M Phase