IRAK1 Antikörper (pSer376)

Produktnummer ABIN742643

Der Kaninchen Polyklonal anti-IRAK1 Antikörper wird verwendet zum Nachweis von IRAK1 in Proben von Human und Maus. Er wurde validiert für WB, ELISA, FACS, IF (cc), IF (p), IHC (p) und IHC (fro).

Kurzübersicht für IRAK1 Antikörper (pSer376) (ABIN742643)

Target: IRAK1 (Interleukin-1 Receptor-Associated Kinase 1 (IRAK1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IRAK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-IRAK1 Antikörper

Bindungsspezifität: pSer376

Kreuzreaktivität: Human, Maus

Homologie: Rat,Dog,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from mouse IRAK1 around the phosphorylation site of Ser376 [QS(p-S)TV]

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu IRAK1

Target: IRAK1 (Interleukin-1 Receptor-Associated Kinase 1 (IRAK1))

Andere Bezeichnung: IRAK1

Hintergrund:

Synonyms: IRAK1 Ser376, IRAK1 S376, IRAK1 p-Ser376, Il1rak, Il1rak, Interleukin 1 receptor associated kinase 1, Interleukin 1 receptor associated kinase 1, Interleukin 1 receptor associated kinase 2, Interleukin-1 receptor-associated kinase 1, IRAK, IRAK-1, IRAK1, IRAK1, IRAK1_HUMAN, IRAK2, IRAK2, mPLK, mPLK, Pelle, Pelle, Pelle homolog, Pelle-like protein kinase, Plpk.

Background: IRAK or Interleukin-1 Receptor-associated Kinase 1, is one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This protein is partially responsible for IL1-induced upregulation of the ubiquitous transcription factor NF-kappa B.

Gen-ID: 16179

Pathways: NF-kappaB Signalweg, TLR Signalweg, Neurotrophin Signalübertragung, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades