Rekombinanter BAX Antikörper (AA 1-100)
Kurzübersicht für Rekombinanter BAX Antikörper (AA 1-100) (ABIN7858063)
Target
Alle BAX Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 1-100
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Verwendungszweck
- Recombinant Bax (Apoptosis Marker) Antibody
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Spezifität
- Recognizes a protein of 21,Ä79 kDa, identified as the Bax protein. This MAb is highly specific to Bax and shows no cross-reaction with Bcl-2 or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and Bax also counters the death repressor activity of Bcl-2.
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Aufreinigung
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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Immunogen
- Recombinant fragment (around aa1-100) of human BAX protein (exact sequence is proprietary)
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Isotyp
- IgG, kappa
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anti-BCL2-Associated X Protein (BAX) (AA 84-175) antibody
BAX Reaktivität: Human, Maus, Ratte, Schwein, Rind (Kuh), Kaninchen, Huhn, Zebrafisch (Danio rerio) WB, ELISA, FACS, IP, IHC (p), IF (p), IF (cc), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-BCL2-Associated X Protein (BAX) (AA 1-100) antibodyBAX Reaktivität: Human WB, IHC, IF, IP Wirt: Kaninchen Polyclonal unconjugated
anti-BCL2-Associated X Protein (BAX) (N-Term) antibodyBAX Reaktivität: Human, Maus, Ratte, Affe, Schwein, Rind (Kuh), Kaninchen, Huhn, Hund, Schaf, Hamster, Pferd, Meerschweinchen, Avian, Cat, Esel, Ziege WB, IF, IHC (p), IHC (fro) Wirt: Ziege Polyclonal unconjugated
anti-BCL2-Associated X Protein (BAX) (AA 41-76) antibodyBAX Reaktivität: Human, Maus WB, FACS Wirt: Kaninchen Polyclonal RB0952 unconjugated
anti-BCL2-Associated X Protein (BAX) (AA 1-158) antibodyBAX Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-BCL2-Associated X Protein (BAX) (AA 1-192) antibodyBAX Reaktivität: Human WB, ELISA, IF, IHC (p), PLA Wirt: Maus Monoclonal 1F5-1B7 unconjugated
anti-BCL2-Associated X Protein (BAX) (AA 13-160) antibodyBAX Reaktivität: Human IHC, ELISA Wirt: Maus Monoclonal 4H9B11 unconjugated
anti-BCL2-Associated X Protein (BAX) antibodyBAX Reaktivität: Human IHC, ELISA, FACS Wirt: Maus Monoclonal 2D8H2 unconjugated
anti-BCL2-Associated X Protein (BAX) antibodyBAX Reaktivität: Human WB, ELISA, FACS Wirt: Maus Monoclonal 2G6B2 unconjugated
anti-BCL2-Associated X Protein (BAX) antibodyKD Validated BAX Reaktivität: Human WB, FACS, IF (p) Wirt: Kaninchen Monoclonal 25GB450 unconjugated Recombinant Antibody
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS
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Konservierungsmittel
- Azide free
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- BAX (BCL2-Associated X Protein (BAX))
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Andere Bezeichnung
- Bax
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Hintergrund
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Apoptosis regulator BAX cytoplasmic isoform beta, Apoptosis regulator BAX membrane isoform alpha, Bax isoform psi, Bax protein cytoplasmic isoform delta, Bax protein cytoplasmic isoform gamma, Bax zeta, Bcl-2-like protein 4, BCL2 associated X protein omega, BCL2 associated X protein transcript variant delta2, BCL2L4
A549, MCF7, HL-60, Jurkat, K562 or HeLa cells. Reed-Sternberg cells in Hodgkin's lymphoma. Intestine, Human Kidney, Human Lung, Human Spleen, Human Stomach.
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Molekulargewicht
- 21kDa
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Gen-ID
- 581, 624291
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UniProt
- Q07812
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Pathways
- p53 Signalweg, PI3K-Akt Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
Target
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