Rekombinanter PDK4 Antikörper

Produktnummer ABIN7828510

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch PDK4 in WB. Es zeigt Reaktivität gegenüber Proben von Maus und Ratte.

Kurzübersicht für Rekombinanter PDK4 Antikörper (ABIN7828510)

Target: PDK4 (Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4))

Antikörpertyp: Recombinant Antibody

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser PDK4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: A735

Produktdetails anti-PDK4 Antikörper

Verwendungszweck: Recombinant PDK4 Monoclonal Antibody

Aufreinigung: Protein A purified

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: WB 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu PDK4

Target: PDK4 (Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4))

Andere Bezeichnung: PDK4

Hintergrund: PDK,PDHK,Pyruvate dehydrogenase lipoamide kinase isozyme,PDK4 PDHK,PDK4,FLJ40832,mitochondrial,Pyruvate dehydrogenase lipoamide kinase isozyme 4,PDK4 PDHK4,PDHK4,[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4,Pyruvate dehydrogenase [lipoamide] kinase isozyme 4 mitochondrial,Pyruvate dehydrogenase kinase 4,Pyruvate dehydrogenase kinase isoenzyme 4,Pyruvate dehydrogenase kinase isoform 4,Pyruvate dehydrogenase kinase isozyme 4,Pyruvate dehydrogenase kinase isozyme 4 mitochondrial,Pyruvate dehydrogenase kinase isoform4 (PDK4) is also named as PDHK4 and belongs to the PDK/BCKDK protein kinase family. It is upregulated by starvation in many tissues of the body during starvation. This causes inactivation of the pyruvate dehydrogenase complex which blocks pyruvate oxidation and conserves lactate and alanine for gluconeogenesis. Enhanced PDK4 expression may be caused by the increase in free fatty acids that occurs during starvation. Free fatty acids can activate peroxisome proliferator-activated receptor α (PPARα), and activation of PPARα can promote PDK4 expression. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molekulargewicht:

Calculated MW: 46 kDa

Observed MW: 44 kDa The actual band is not consistent with the expectation.

UniProt: Q16654

Pathways: PI3K-Akt Signalweg, Hedgehog Signalweg, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effekt