Rekombinanter PIK3R1 Antikörper

Produktnummer ABIN7828456

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch PIK3R1 in IHC und IF. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für Rekombinanter PIK3R1 Antikörper (ABIN7828456)

Target: PIK3R1 (PI3K p85a) (Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser PIK3R1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF)

Klon: A332

Produktdetails anti-PIK3R1 Antikörper

Verwendungszweck: Recombinant PI3 Kinase p85 alpha Monoclonal Antibody

Aufreinigung: Protein A purified

Immunogen: Recombinant human PI3 Kinase p85 alpha fragment

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:100,IF 1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu PIK3R1

Target: PIK3R1 (PI3K p85a) (Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a))

Andere Bezeichnung: PI3 Kinase p85 alpha

Hintergrund: GRB,IMD,AGM,PIK3R,AGM7,GRB1,IMD36,p85,p85-ALPHA,PI3 Kinase p85 alpha,PIK3R1,p85 alpha,P85A,Phosphatidylinositol 3 kinase,Phosphatidylinositol 3 kinase associated p 85 alpha,Phosphatidylinositol 3 kinase regulatory 1,Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha,Phosphatidylinositol 3-kinase regulatory subunit alpha,Phosphoinositide 3 kinase,PI3 kinase p85 subunit alpha,PI3K,PI3K regulatory subunit alpha,PI3-kinase regulatory subunit alpha,PI3-kinase subunit p85-alpha,polypeptide 1 (p85 alpha),PtdIns 3 kinase p85 alpha,PtdIns-3-kinase regulatory subunit alpha,PtdIns-3-kinase regulatory subunit p85-alpha,regulatory subunit,regulatory subunit 1 (alpha),Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling. Modulates the cellular response to ER stress by promoting nuclear translocation of XBP1 isoform 2 in a ER stress- and/or insulin-dependent manner during metabolic overloading in the liver and hence plays a role in glucose tolerance improvement. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

UniProt: P27986

Pathways: T-Zell Rezeptor Signalweg, Response to Growth Hormone Stimulus, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Hepatitis C, Protein targeting to Nucleus, VEGF Signaling, BCR Signaling, Warburg Effekt