Rekombinanter Src Antikörper (pTyr419)

Produktnummer ABIN7800050

Dieser Kaninchen Monoklonal Antikörper erkennt spezifisch Src in WB und FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Rekombinanter Src Antikörper (pTyr419) (ABIN7800050)

Target: Src (Proto-oncogene tyrosine-protein kinase Src (Src))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Src Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Güteklasse: KD Validated

Klon: 23GB4080

Produktdetails anti-Src Antikörper

Bindungsspezifität: pTyr419

Expressionssystem: HEK-293 Cells

Verwendungszweck: KD-Validated Phospho-Src (Y419) Recombinant Rabbit mAb

Kreuzreaktivität: Maus, Ratte

Aufreinigung: Affinity Purified

Immunogen: A synthesized peptide derived from human Phospho-Src (Y419)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western Blotting (WB): 1:1,000-1:5,000, Flow Cytometry (FCM): 1:200-1:2,000

Kommentare:

We assess the antibodies’ specificity and selectivity using knockdown techniques. Our validation approach is straightforward: if an antibody identifies a signal in wild-type (WT) cells, but this signal is absent or noticeably reduced in gene-silenced (KD) cells, we consider the antibody to be highly specific.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, with 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C for one year.

Haltbarkeit: 12 months

Details zu Src

Target: Src (Proto-oncogene tyrosine-protein kinase Src (Src))

Andere Bezeichnung: Src

Molekulargewicht: 60 kDa

Gen-ID: 6714

UniProt: P12931

Pathways: JAK-STAT Signalweg, Neurotrophin Signalübertragung, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process, Autophagie, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling, Platelet-derived growth Factor Receptor Signaling, Thromboxane A2 Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling