Complement C4 Antikörper (Chain alpha)
Kurzübersicht für Complement C4 Antikörper (Chain alpha) (ABIN7672925)
Target
Alle Complement C4 (C4) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Chain alpha
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Verwendungszweck
- C4 antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
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Immunogen sequence: 1028-1336
Immunogen: complement component 4A(Rodgers blood group)
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:1000-1:6000, IHC: 1:50-1:500
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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Haltbarkeit
- 12 months
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- Complement C4 (C4) (Complement 4 (C4))
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Andere Bezeichnung
- C4
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Hintergrund
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Synonyms: Complement C4-A|Acidic complement C4|C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2|Complement C4 beta chain|Complement C4-A alpha chain|C4a anaphylatoxin|C4b-A|C4d-A|Complement C4 gamma chain|C4A|CO4|CPAMD2
Background: Complement C4, a component of the classical complement pathway, has an important role in innate immune function. C4 protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains (molecular wights 95, 78, and 31 kDa) prior to secretion. The alpha chain is cleaved to release C4 anaphylatoxin, an antimicrobial peptide and a mediator of local inflammation. This antibody can recognize C4 precursor, C4 alpha chain, C4b, and C4d.
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Molekulargewicht
- 95 kDa
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Gen-ID
- 720
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UniProt
- P0C0L4
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Pathways
- Komplementsystem
Target
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