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Complement C4 Antikörper (Complement 4) AA 701-800 Primary Antibody

C4 Reaktivität: Human ELISA, IF (cc), IF (p), IHC (fro), IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1385186
$374.00
Zzgl. Versandkosten $45.00
100 μL
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 4 bis 6 Werktagen
  • Target Alle Complement C4 (C4) Antikörper anzeigen
    Complement C4 (C4)
    Bindungsspezifität
    • 15
    • 14
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 701-800
    Reaktivität
    • 57
    • 6
    • 4
    • 1
    Human
    Wirt
    • 47
    • 8
    • 5
    • 3
    • 3
    • 2
    Kaninchen
    Klonalität
    • 60
    • 8
    Polyklonal
    Konjugat
    • 34
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Dieser Complement C4 Antikörper ist unkonjugiert
    Applikation
    • 25
    • 25
    • 20
    • 13
    • 12
    • 11
    • 9
    • 7
    • 6
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    Human
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Complement C4 C4a anaphylatoxin or complement C4 alpha chain
    Isotyp
    IgG
  • Applikationshinweise
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    Complement C4 (C4)
    Andere Bezeichnung
    Complement C4/C4 (C4 Produkte)
    Synonyme
    C4B1, C4B12, C4B2, C4B3, C4B5, C4BD, C4B_2, C4F, CH, CO4, CPAMD3, C4, C4A2, C4A3, C4A4, C4A6, C4AD, C4S, CPAMD2, RG, C4-1, C4b, C4-2, Slp, Ss, complement C4B (Chido blood group), complement C4A (Rodgers blood group), complement component 4A (Rodgers blood group), complement 4, complement component 4A, complement component 4B (Chido blood group), C4B, C4A, C4a, C4, C4b
    Hintergrund

    This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011].

    Subcellular location: Secreted

    Synonyms: C4a anaphylatoxin, Complement C4-A alpha chain, complement C4-A proprotein, Acidic C4, Acidic complement C4, Basic C4, Basic complement C4, C4 Anaphylatoxin, C4 complement C4d region, complement C4 alpha chain, C4A, C4A13, C4A2, C4A3, C4A4, C4A6, C4A91, C4B, C4B1, C4B12, C4B2, C4B3, C4B5, C4F, C4S, CH, Chido form of C4, CO4, Complement C4 A, Complement C4 B, Complement C4B, Complement component 4A Rodgers blood group, Complement component 4A, Complement component 4B Childo blood group, Complement component 4B, Complement component C4B, CPAMD2, CPAMD3. RG, Rodgers Form Of C4.

    Gen-ID
    720, 721
    Pathways
    Komplementsystem
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