IL-18 Antikörper

Produktnummer ABIN7670661

Der Kaninchen Polyklonal Anti-IL-18-Antikörper wurde für ELISA validiert. Er ist geeignet, IL-18 in Proben von Human zu detektieren.

Kurzübersicht für IL-18 Antikörper (ABIN7670661)

Target: IL-18 (IL18) (Interleukin 18 (IL18))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL-18 Antikörper ist unkonjugiert

Applikation: ELISA

Produktdetails anti-IL-18 Antikörper

Verwendungszweck: IL-18/IL-1F4 Polyclonal Antibody(Capture/Detector)

Aufreinigung: Antigen Affinity Purification

Immunogen: Recombinant Human IL-18/IL-1F4 protein expressed by E.coli

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA Capture 2-8 μg/mL,ELISA Detector 0.1-0.4 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Sterile PBS , pH 7.4

Konservierungsmittel: Without preservative

Handhabung: Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C Valid for 1 month or -20°C Valid for 12 months

Haltbarkeit: 12 months

Details zu IL-18

Target: IL-18 (IL18) (Interleukin 18 (IL18))

Andere Bezeichnung: IL-18/IL-1F4

Hintergrund: IL18,IL-18, IGIF, IL1F4,Iboctadekin,Interferon gamma-inducing factor,InterLeukin-1 gamma (IL-1 gamma),Pro-inflammatory cytokine primarily involved in epithelial barrier repair,polarized T-helper 1 (Th1) cell and natural killer (NK) cell immune responses.Upon binding to Il18R1 and Il18RAP,forms a signaling ternary complex which activates NF-kappa-B,triggering synthesis of inflammatory mediators.Synergizes with Il12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells and natural killer (NK) cells.Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore.

UniProt: Q14116

Pathways: Cellular Response to Molecule of Bacterial Origin, Activated T Cell Proliferation, Cancer Immune Checkpoints, Inflammasome