Der Kaninchen Polyklonal Anti-Complement Factor H-Antikörper wurde für ELISA validiert. Er ist geeignet, Complement Factor H in Proben von Human zu detektieren.
Produktnummer ABIN7670580
Kurzübersicht für Complement Factor H Antikörper (ABIN7670580)
Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store at 4°C Valid for 1 month or -20°C Valid for 12 months
Haltbarkeit
12 months
Target
Complement Factor H (CFH)
Andere Bezeichnung
Complement Factor H/CFH
Hintergrund
CF-H,AHUS1,AMBP1,FH,FHL1,ARMD4,ARMS1,CFHL3,HF,HF1,HF2,HUS,Complement factor H (CFH) is an abundant plasma glycoprotein that regulates the function of the alternative complement pathway in fluid phase and on cellular surfaces. Factor H binds to C3b,accelerates the decay of the alternative pathway C3-convertase (C3bBb) and acts as a cofactor for the factor I-mediated proteolytic inactivation of C3b. It plays a critical role in the homeostasis of the complement system in plasma and in the protection of bystander host cells and tissues from damage by complement activation. Abnormalities in factor H have been associated with renal disease.