Calnexin Antikörper (AA 501-592)

Produktnummer ABIN733073

Der Kaninchen Polyklonal Anti-Calnexin-Antikörper wurde für WB, ELISA, FACS, IHC (p), IF (cc), IF (p) und IHC (fro) validiert. Er ist geeignet, Calnexin in Proben von Maus und Ratte zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für Calnexin Antikörper (AA 501-592) (ABIN733073)

Target: Calnexin (CANX)

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Calnexin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-Calnexin Antikörper

Bindungsspezifität: AA 501-592

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Cow,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CANX

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-Calnexin Antikörper (ABIN733073)

Correani, Di Francesco, Mignogna, Fabrizi, Leone, Giorgi, Passeri, Casata, Fumagalli, Maras, Schininà: "Plasma Membrane Protein Profiling in Beta-Amyloid-Treated Microglia Cell Line." in: Proteomics, Vol. 17, Issue 17-18, (2017) (PubMed).

Details zu Calnexin

Target: Calnexin (CANX)

Andere Bezeichnung: CANX/Calnexin

Hintergrund:

Synonyms: CNX, P90, IP90, Calnexin, Major histocompatibility complex class I antigen-binding protein p88, CANX

Background: Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at the synapse.

Gen-ID: 821

UniProt: P27824

Pathways: MAPK Signalweg, Thyroid Hormone Synthesis