Calnexin Antikörper (N-Term) (CF®740)
Kurzübersicht für Calnexin Antikörper (N-Term) (CF®740) (ABIN7650426)
Target
Alle Calnexin (CANX) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 1-300, N-Term
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Verwendungszweck
- Calnexin (Endoplasmic Reticulum Marker) (CANX/1543), CF740 conjugate
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Produktmerkmale
- Calnexin is a type-I integral membrane protein of the endoplasmic reticulum (ER). It is a calcium-binding chaperone protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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Immunogen
- Recombinant N-terminal fragment of human Calnexin protein (around aa 1-300)
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Isotyp
- IgG1, kappa
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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Positive Control: HeLa, MCF-7 or U2OS cells. Kidney or small intestine.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.1 mg/mL
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Buffer
- PBS, 0.1 % rBSA, 0.05 % azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Protect from light
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Lagerung
- 4 °C
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Informationen zur Lagerung
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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Haltbarkeit
- 24 months
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- Calnexin (CANX)
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Andere Bezeichnung
- Calnexin
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Hintergrund
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Synonyms: Calnexin, CANX, IP90, Major histocompatibility complex class I antigen-binding protein p88
Gene Symbol: CANX
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Molekulargewicht
- 67 kDa (predicted), 80-90 kDa (observed)
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Gen-ID
- 821
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UniProt
- P27824
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Pathways
- MAPK Signalweg, Thyroid Hormone Synthesis
Target
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