XBP1 Antikörper

Produktnummer ABIN7606725

Dieses Kaninchen Monoklonal-Antikörper erkennt spezifisch XBP1 in WB, IHC, FACS, IF und ICC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für XBP1 Antikörper (ABIN7606725)

Target: XBP1 (X-Box Binding Protein 1 (XBP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser XBP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Immunocytochemistry (ICC)

Klon: AAAF-24

Produktdetails anti-XBP1 Antikörper

Verwendungszweck: Anti-XBP1 Rabbit Monoclonal Antibody

Produktmerkmale: Anti-XBP1 Rabbit Monoclonal Antibody (ABIN7606725). Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human.

Aufreinigung: Affinity-chromatography

Immunogen: A synthesized peptide derived from human XBP1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000
IHC 1:100-1:500
ICC/IF 1:50-1:200
FC 1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Konzentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Details zu XBP1

Target: XBP1 (X-Box Binding Protein 1 (XBP1))

Andere Bezeichnung: XBP1

Hintergrund:

Synonyms: X-box-binding protein 1 ,XBP-1 ,Tax-responsive element-binding protein 5 ,TREB-5 ,X-box-binding protein 1, cytoplasmic form ,X-box-binding protein 1, luminal form ,XBP1 ,TREB5 , XBP2 ,

Tissue Specificity: Expressed in plasma cells in rheumatoid synovium (PubMed:11460154). Over-expressed in primary breast cancer and metastatic breast cancer cells (PubMed:25280941). Isoform 1 and isoform 2 are expressed at higher level in proliferating as compared to confluent quiescent endothelial cells (PubMed:19416856). .

Molekulargewicht: 100-110 kDa

UniProt: P17861

Pathways: ER-Nucleus Signaling, Unfolded Protein Response