RAD50 Antikörper

Produktnummer ABIN7606123

Der Kaninchen Monoklonal Anti-RAD50-Antikörper wurde für WB, ICC und IF validiert. Er ist geeignet, RAD50 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für RAD50 Antikörper (ABIN7606123)

Target: RAD50 (RAD50 Homolog (S. Cerevisiae) (RAD50))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser RAD50 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Klon: ACCG-18

Produktdetails anti-RAD50 Antikörper

Verwendungszweck: Anti-Rad50 Monoclonal Antibody

Produktmerkmale: Anti-Rad50 Monoclonal Antibody (ABIN7606123). Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Aufreinigung: Affinity-chromatography

Immunogen: A synthesized peptide derived from human Rad50 Component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11A.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000
ICC/IF 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Konzentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Details zu RAD50

Target: RAD50 (RAD50 Homolog (S. Cerevisiae) (RAD50))

Andere Bezeichnung: RAD50

Hintergrund:

Synonyms: Ubiquitin-like modifier-activating enzyme ATG7,ATG12-activating enzyme E1 ATG7,Autophagy-related protein 7,APG7-like,hAGP7,Ubiquitin-activating enzyme E1-like protein,ATG7,APG7L,

Tissue Specificity: Widely expressed, especially in kidney, liver, lymph nodes and bone marrow. .

Molekulargewicht: 35 kDa

UniProt: Q92878

Pathways: DNA Reparatur, Protein targeting to Nucleus