GZMB Antikörper
Kurzübersicht für GZMB Antikörper (ABIN7605016)
Target
Alle GZMB Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Verwendungszweck
- Anti-Granzyme B GZMB Monoclonal Antibody
-
Produktmerkmale
- Anti-Granzyme B GZMB Monoclonal Antibody-1. Tested in IHC, ICC/IF, IP applications. This antibody reacts with Human.
-
Aufreinigung
- Affinity-chromatography
-
Immunogen
- A synthesized peptide derived from human Granzyme B This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- IHC 1:50-1:200ICC/IF 1:50-1:200IP 1:50
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 0.5 mg/mL
-
Buffer
- Rabbit IgG in stabilizing components, phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C,-20 °C
-
Informationen zur Lagerung
- Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
-
Haltbarkeit
- 12 months
-
-
- GZMB (Granzyme B (GZMB))
-
Andere Bezeichnung
- GZMB
-
Hintergrund
- Granzyme B
-
Molekulargewicht
- 23 kDa
-
Gen-ID
- 3002
-
UniProt
- P10144
-
Pathways
- Apoptose, Caspase Kaskade in der Apoptose
Target
-