EIF2AK2 Antikörper (pThr446)

Produktnummer ABIN7603398

Dieses Kaninchen Monoklonal-Antikörper erkennt spezifisch EIF2AK2 in WB, IHC und IP. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für EIF2AK2 Antikörper (pThr446) (ABIN7603398)

Target: EIF2AK2 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser EIF2AK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Klon: BIC-5

Produktdetails anti-EIF2AK2 Antikörper

Bindungsspezifität: pThr446

Verwendungszweck: Anti-Phospho-PKR (T446) EIF2AK2 Rabbit Monoclonal Antibody

Produktmerkmale: Anti-Phospho-PKR EIF2AK2 Rabbit Monoclonal Antibody (ABIN7603398). Tested in WB, IHC, IP applications. This antibody reacts with Human.

Aufreinigung: Affinity-chromatography

Immunogen: A synthesized peptide derived from human Phospho-PKR (T446)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000
IHC 1:50-1:200
IP 1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Details zu EIF2AK2

Target: EIF2AK2 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2))

Andere Bezeichnung: EIF2AK2

Hintergrund:

Synonyms: Interferon-induced, double-stranded RNA-activated protein kinase,2.7.11.1,Eukaryotic translation initiation factor 2-alpha kinase 2,eIF-2A protein kinase 2,Interferon-inducible RNA-dependent protein kinase,P1/eIF-2A protein kinase,Protein kinase RNA-activated,PKR,Protein kinase R ,Tyrosine-protein kinase EIF2AK2,2.7.10.2,p68 kinase,EIF2AK2,PKR, PRKR,

Tissue Specificity: Highly expressed in thymus, spleen and bone marrow compared to non-hematopoietic tissues such as small intestine, liver, or kidney tissues. Colocalizes with GSK3B and TAU in the Alzheimer disease (AD) brain. Elevated levels seen in breast and colon carcinomas,and which correlates with tumor progression and invasiveness or risk of progression. .

Molekulargewicht: 39 kDa

UniProt: P19525

Pathways: DNA Reparatur, ER-Nucleus Signaling, Hepatitis C