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Mesp2 Antikörper (AA 1-397)

Der Kaninchen Polyklonal Anti-Mesp2-Antikörper wurde für ELISA, WB, IF, FACS, ICC und IHC validiert. Er ist geeignet, Mesp2 in Proben von Human zu detektieren.
Produktnummer ABIN7599353

Kurzübersicht für Mesp2 Antikörper (AA 1-397) (ABIN7599353)

Target

Alle Mesp2 Antikörper anzeigen
Mesp2 (Mesoderm Posterior 2 Homolog (Mesp2))

Reaktivität

  • 6
  • 4
  • 2
Human

Wirt

  • 6
  • 4
Kaninchen

Klonalität

  • 6
  • 4
Polyklonal

Konjugat

  • 10
Dieser Mesp2 Antikörper ist unkonjugiert

Applikation

ELISA, Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1-397

    Verwendungszweck

    Anti-Mesp2 Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins.

    Produktmerkmale

    Anti-Mesp2 Antibody Picoband® (ABIN7599353). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E.coli-derived human Mesp2 recombinant protein (Position: M1-Y397).

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.25-0.5 μg/mL, Human
    Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Cornier, A. S., Staehling-Hampton, K., Delventhal, K. M., Saga, Y., Caubet, J.-F., Sasaki, N., Ellard, S., Young, E., Ramirez, N., Carlo, S. E., Torres, J., Emans, J. B., Turnpenny, P. D., Pourquie, O. Mutations in the MESP2 gene cause spondylothoracic dysostosis/Jarcho-Levin syndrome. Am. J. Hum. Genet. 82: 1334-1341, 2008. 2. Morimoto, M., Takahashi, Y., Endo, M., Saga, Y. The Mesp2 transcription factor establishes segmental borders by suppressing Notch activity. Nature 435: 354-359, 2005. 3. Saga, Y., Hata, N., Koseki, H., Taketo, M. M. Mesp2: a novel mouse gene expressed in the presegmented mesoderm and essential for segmentation initiation. Genes Dev. 11: 1827-1839, 1997.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target

    Mesp2 (Mesoderm Posterior 2 Homolog (Mesp2))

    Andere Bezeichnung

    MESP2

    Hintergrund

    Synonyms: Forkhead box protein F1, Forkhead-related activator 1, FREAC-1, Forkhead-related protein FKHL5, Forkhead-related transcription factor 1, FOXF1, FKHL5, FREAC1

    Tissue Specificity: Expressed in kidney.

    Background: Mesoderm posterior protein 2 (MESP2), also known as class C basic helix-loop-helix protein 6 (bHLHc6), is a protein that in humans is encoded by the MESP2 gene. This gene encodes a member of the bHLH family of transcription factors and plays a key role in defining the rostrocaudal patterning of somites via interactions with multiple Notch signaling pathways. This gene is expressed in the anterior presomitic mesoderm and is downregulated immediately after the formation of segmented somites. This gene also plays a role in the formation of epithelial somitic mesoderm and cardiac mesoderm. Mutations in the MESP2 gene cause autosomal recessive spondylocostal dystosis 2 (SCD02).

    Molekulargewicht

    45 kDa

    Gen-ID

    145873
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