Mesp2 Antikörper (AA 220-300)

Produktnummer ABIN7229648

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Mesp2 in ELISA und WB. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für Mesp2 Antikörper (AA 220-300) (ABIN7229648)

Target: Mesp2 (Mesoderm Posterior 2 Homolog (Mesp2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Mesp2 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Produktdetails anti-Mesp2 Antikörper

Bindungsspezifität: AA 220-300

Verwendungszweck: Rabbit Anti-MESP2 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of MESP2 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human MESP2 protein at AA range: 220-300

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Mesp2

Target: Mesp2 (Mesoderm Posterior 2 Homolog (Mesp2))

Andere Bezeichnung: MESP2

Hintergrund: Mesoderm posterior protein 2, Class C basic helix-loop-helix protein 6, bHLHc6MESP2 (Mesoderm Posterior BHLH Transcription Factor 2) is a Protein Coding gene. Diseases associated with MESP2 include Spondylocostal Dysostosis 2, Autosomal Recessive and Spondylocostal Dysostosis, Autosomal Recessive. Among its related pathways are Cardiac Progenitor Differentiation and Gene regulatory network modelling somitogenesis. MESP2 encodes a member of the bHLH family of transcription factors and plays a key role in defining the rostrocaudal patterning of somites via interactions with multiple Notch signaling pathways. MESP2 is expressed in the anterior presomitic mesoderm and is downregulated immediately after the formation of segmented somites. MESP2 also plays a role in the formation of epithelial somitic mesoderm and cardiac mesoderm. Mutations in the MESP2 gene cause autosomal recessive spondylocostal dystosis 2 (SCD02).

Molekulargewicht: 43kD

Gen-ID: 145873

UniProt: Q0VG99