Mesp2 Antikörper (AA 37-94)
Kurzübersicht für Mesp2 Antikörper (AA 37-94) (ABIN1098148)
Target
Alle Mesp2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 37-94
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Verwendungszweck
- MESP2 Antibody
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Aufreinigung
- Purified antibody
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Immunogen
- Purified recombinant fragment of human MESP2 (AA: 37-94 ) expressed in E. Coli.
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Isotyp
- IgG1
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Applikationshinweise
- ELISA: 1/10000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Mutation analysis of MESP2, HES7 and DUSP6 gene exons in patients with congenital scoliosis." in: Studies in health technology and informatics, Vol. 176, pp. 52-5, (2012) (PubMed).
: "Mutations in the MESP2 gene cause spondylothoracic dysostosis/Jarcho-Levin syndrome." in: American journal of human genetics, Vol. 82, Issue 6, pp. 1334-41, (2008) (PubMed).
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- Mesp2 (Mesoderm Posterior 2 Homolog (Mesp2))
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Andere Bezeichnung
- MESP2
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Hintergrund
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This gene encodes a member of the bHLH family of transcription factors and plays a key role in defining the rostrocaudal patterning of somites via interactions with multiple Notch signaling pathways. This gene is expressed in the anterior presomitic mesoderm and is downregulated immediately after the formation of segmented somites. This gene also plays a role in the formation of epithelial somitic mesoderm and cardiac mesoderm. Mutations in the MESP2 gene cause autosomal recessive spondylocostal dystosis 2 (SCD02).
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Molekulargewicht
- 41.8 kDa
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Gen-ID
- 145873
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UniProt
- Q0VG99
Target
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