Mesp2 Antikörper (AA 218-397)

Produktnummer ABIN7159423

Produktdetails anti-Mesp2 Antikörper

Target: Mesp2 (Mesoderm Posterior 2 Homolog (Mesp2))

Bindungsspezifität: AA 218-397

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Mesp2 Antikörper ist unkonjugiert

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Mesoderm posterior protein 2 protein (218-397AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Mesp2

Target: Mesp2 (Mesoderm Posterior 2 Homolog (Mesp2))

Andere Bezeichnung: MESP2 (Mesp2 Produkte)

Synonyme: bHLHc6 antikoerper, SCDO2 antikoerper, mesoderm posterior 2 antikoerper, mesoderm posterior bHLH transcription factor 2 antikoerper, Mesp2 antikoerper, MESP2 antikoerper

Hintergrund:

Background: Transcription factor with important role in somitogenesis. Defines the rostrocaudal patterning of the somite by participating in distinct Notch pathways. Regulates also the FGF signaling pathway. Specifies the rostral half of the somites. Generates rostro-caudal polarity of somites by down-regulating in the presumptive rostral domain DLL1, a Notch ligand. Participates in the segment border formation by activating in the anterior presomitic mesoderm LFNG, a negative regulator of DLL1-Notch signaling. Acts as a strong suppressor of Notch activity. Together with MESP1 is involved in the epithelialization of somitic mesoderm and in the development of cardiac mesoderm.

Aliases: Basic helix loop helix protein MESP 2 antibody, Basic helix loop helix protein MESP2 antibody, BHLH protein MesP2 antibody, bHLHc6 antibody, Class C basic helix-loop-helix protein 6 antibody, Hypothetical class II basic helix loop helix protein MESP 2 antibody, Hypothetical class II basic helix loop helix protein MESP2 antibody, Mesoderm posterior 2 antibody, mesoderm posterior 2 homolog (mouse) antibody, Mesoderm posterior 2 homolog antibody, Mesoderm posterior protein 2 antibody, Mesp 2 antibody, MESP2 antibody, MESP2_HUMAN antibody, SCDO 2 antibody, SCDO2 antibody

UniProt: Q0VG99