Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycero
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C,-80 °C
Informationen zur Lagerung
Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
Target
VAMP2
(Vesicle-Associated Membrane Protein 2 (Synaptobrevin 2) (VAMP2))
Andere Bezeichnung
VAMP-2
Hintergrund
Synaptobrevin 2 (Vesicle-associated membrane, VAMP2), which is an 18 kDa integral membrane proteinlocalized to the cytoplasmic surface of synaptic vesicle, consists of a proline-rich N-terminal region, a highlyconserved hydrophilic domain, followed by a transmembrane anchor and a C-terminal tail. Synaptobrevin 2 ispredominantly expressed in Langerhans islets and glomerular cells. The N-terminal domain of the protein forms aspecific SNARE complex with the target membrane-associated t- or Q-SNAREs syntaxin 1 and SNAP-25.This antibody recognizes specifically synaptobrevin 2, but it also shows a low affinity to synaptobrevin1.