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TGFB1 Antikörper (AA 351-390)

Der Kaninchen Polyklonal Anti-TGFB1-Antikörper wurde für WB, ELISA, FACS, IHC (p), IF (p), IF (cc) und IHC (fro) validiert. Er ist geeignet, TGFB1 in Proben von Human, Maus, Ratte, Schaf und Kaninchen zu detektieren. Es sind 16+ Publikationen verfügbar.
Produktnummer ABIN724685

Kurzübersicht für TGFB1 Antikörper (AA 351-390) (ABIN724685)

Target

Alle TGFB1 Antikörper anzeigen
TGFB1 (Transforming Growth Factor, beta 1 (TGFB1))

Reaktivität

  • 164
  • 92
  • 61
  • 24
  • 22
  • 18
  • 18
  • 13
  • 11
  • 8
  • 7
  • 6
  • 5
  • 5
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
Human, Maus, Ratte, Schaf, Kaninchen

Wirt

  • 196
  • 78
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
Kaninchen

Klonalität

  • 196
  • 89
Polyklonal

Konjugat

  • 157
  • 41
  • 32
  • 10
  • 6
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
Dieser TGFB1 Antikörper ist unkonjugiert

Applikation

  • 215
  • 135
  • 103
  • 83
  • 80
  • 35
  • 35
  • 26
  • 25
  • 14
  • 11
  • 8
  • 6
  • 5
  • 5
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Bindungsspezifität

    • 61
    • 15
    • 15
    • 9
    • 9
    • 8
    • 7
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 351-390

    Kreuzreaktivität

    Human, Maus, Kaninchen, Ratte, Schaf

    Homologie

    Dog,Cow,Pig,Guinea Pig

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human TGF-Beta 1

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    Haltbarkeit

    12 months
  • Shang, Liu, Liu, Li, Dou, Zhang, Sun, Zhang, Zhu, Mu, Ding, Wen: "Telmisartan improves vascular remodeling through ameliorating prooxidant and profibrotic mechanisms in hypertension via the involvement of transforming growth factor-β1." in: Molecular medicine reports, Vol. 16, Issue 4, pp. 4537-4544, (2018) (PubMed).

    Mao, Zhang, Qi, Jiang, Wu, Lu, Ainiwaer, Shang, Xu, Hao, Shou, Li, Li, Zhang, Bao, Wen: "Efficacy of radiotherapy for the treatment of cystic echinococcosis in naturally infected sheep." in: Infectious diseases of poverty, Vol. 6, Issue 1, pp. 88, (2017) (PubMed).

    Shen, Wu, Wang, Zhao, Zhang, Li, Zhao: "Chloroquine attenuates paraquat-induced lung injury in mice by altering inflammation, oxidative stress and fibrosis." in: International immunopharmacology, Vol. 46, pp. 16-22, (2017) (PubMed).

    Eren, Turgut, Akin, Demir: "The Suppression of Wound Healing Response with Sirolimus and Sunitinib Following Experimental Trabeculectomy in a Rabbit Model." in: Current eye research, Vol. 41, Issue 3, pp. 367-76, (2016) (PubMed).

    Xue, Chen, Zhao, Zhao, Duan, Zheng: "The Overexpression of TGF-β and CCN2 in Intrauterine Adhesions Involves the NF-κB Signaling Pathway." in: PLoS ONE, Vol. 10, Issue 12, pp. e0146159, (2016) (PubMed).

    Venter, Marques, Santos, Monte-Alto-Costa: "Use of platelet-rich plasma in deep second- and third-degree burns." in: Burns : journal of the International Society for Burn Injuries, Vol. 42, Issue 4, pp. 807-14, (2016) (PubMed).

    Ganguly, Wen, Myer, Czech, Sahu, Steinmetz, Raman: "Anti-atherogenic effect of trivalent chromium-loaded CPMV nanoparticles in human aortic smooth muscle cells under hyperglycemic conditions in vitro." in: Nanoscale, Vol. 8, Issue 12, pp. 6542-54, (2016) (PubMed).

    Zhu, Hu, Yu, Ren, Hu: "High Molecular Weight Hyaluronic Acid Inhibits Fibrosis of Endometrium." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 22, pp. 3438-3445, (2016) (PubMed).

    Du, Niu, Wang, Zhao, Kong, Zhang, Nan: "TLR4‑dependent signaling pathway modulation: A novel mechanism by which pioglitazone protects against nutritional fibrotic steatohepatitis in mice." in: Molecular medicine reports, Vol. 13, Issue 3, pp. 2159-66, (2016) (PubMed).

    Shang, Liu, Liu, Zhang, Mu, Zhu, Liang, Zhai, Ding, Li, Wen: "Acetyl-11-Keto-β-Boswellic Acid Attenuates Prooxidant and Profibrotic Mechanisms Involving Transforming Growth Factor-β1, and Improves Vascular Remodeling in Spontaneously Hypertensive Rats." in: Scientific reports, Vol. 6, pp. 39809, (2016) (PubMed).

    Tang, Jiang, Zhou, Xia, Dai: "Increased adenosine levels contribute to ischemic kidney fibrosis in the unilateral ureteral obstruction model." in: Experimental and therapeutic medicine, Vol. 9, Issue 3, pp. 737-743, (2015) (PubMed).

    Hu, Zeng, Jiang, Hu, Meng, Zhu, Mao: "The expression of marker for endometrial stem cell and fibrosis was increased in intrauterine adhesious." in: International journal of clinical and experimental pathology, Vol. 8, Issue 2, pp. 1525-34, (2015) (PubMed).

    Sun, Li, Wen, Wang, Ji, Ma: "Immunological effect induced by mesenchymal stem cells in a rat liver transplantation model." in: Experimental and therapeutic medicine, Vol. 10, Issue 2, pp. 401-406, (2015) (PubMed).

    Abdelmagid, Belcher, Moussa, Lababidi, Sondag, Novak, Sanyurah, Frara, Razmpour, Del Carpio-Cano, Safadi: "Mutation in osteoactivin decreases bone formation in vivo and osteoblast differentiation in vitro." in: The American journal of pathology, Vol. 184, Issue 3, pp. 697-713, (2014) (PubMed).

    Erbas, Yapislar, Oltulu, Yavaso?lu, Aktug, Taskiran: "Nephro-protective effect of granulocyte colony-stimulating factor in streptozotocin induced diabetic rats." in: Biotechnic & histochemistry : official publication of the Biological Stain Commission, Vol. 89, Issue 7, pp. 488-96, (2014) (PubMed).

    Kou, Hu, Yao, Wang, Shen, Kang, Hong: "Transforming growth factor-?1 promotes Treg commitment in nasal polyposis after intranasal steroid treatment." in: Inflammation research : official journal of the European Histamine Research Society ... [et al.], Vol. 62, Issue 3, pp. 283-9, (2013) (PubMed).

  • Target

    TGFB1 (Transforming Growth Factor, beta 1 (TGFB1))

    Andere Bezeichnung

    TGF beta 1

    Hintergrund

    Synonyms: CED, DPD1, TGFB, TGFbeta, Transforming growth factor beta-1, TGF-beta-1, TGFB1

    Background: Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts.

    Molekulargewicht

    12.8kDa

    Gen-ID

    7040

    UniProt

    P01137

    Pathways

    EGFR Signaling Pathway, Dopaminergic Neurogenesis, Cellular Response to Molecule of Bacterial Origin, Glycosaminoglycan Metabolic Process, Regulation of Leukocyte Mediated Immunity, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Ribonucleoside Biosynthetic Process, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagie, Cancer Immune Checkpoints
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