TGFB1 Antikörper (Middle Region)

Produktnummer ABIN2780306

Der Kaninchen Polyklonal anti-TGFB1 Antikörper (ABIN2780306) detektiert spezifisch TGFB1 in WB, IHC und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Ratte, Maus, Rind (Kuh), Schwein, Meerschweinchen, Hund, Schaf, Pferd und Ziege.

Kurzübersicht für TGFB1 Antikörper (Middle Region) (ABIN2780306)

Target: TGFB1 (Transforming Growth Factor, beta 1 (TGFB1))

Reaktivität: Ratte, Maus, Rind (Kuh), Schwein, Meerschweinchen, Hund, Schaf, Pferd, Ziege

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TGFB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-TGFB1 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: TGFB1 Antibody - middle region

Sequenz: DTPEWLSFDV TGVVRQWLNQ GDGIQGFRFS AHCSCDSKDN KLHVEINGIS

Homologie: Cow: 79%, Dog: 79%, Goat: 79%, Guinea Pig: 87%, Horse: 79%, Mouse: 100%, Pig: 93%, Rat: 93%, Sheep: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against TGFB1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of mouse TGFB1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8114247

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu TGFB1

Target: TGFB1 (Transforming Growth Factor, beta 1 (TGFB1))

Andere Bezeichnung: TGFB1

Hintergrund:

Background Information: Tgfb1 is a multifunctional protein that control proliferation, differentiation, and other functions in many cell types. Many cells synthesize TGFB1 and essentially all of them have specific receptors for this protein. It regulates the actions of many other growth factors and determines a positive or negative direction of their effects. It plays an important role in bone remodelling. It is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts.

Gene Name: Transforming growth factor, beta 1

Alternative Symbols: Tgfb, Tgfb-1, TGFbeta, TGF-beta, TGFbeta1, TGF-beta1

Protein Name: Transforming growth factor beta-1

Molekulargewicht: 43kDa

Gen-ID: 21803

NCBI Accession: NP_035707

UniProt: P04202

Pathways: EGFR Signaling Pathway, Dopaminergic Neurogenesis, Cellular Response to Molecule of Bacterial Origin, Glycosaminoglycan Metabolic Process, Regulation of Leukocyte Mediated Immunity, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Ribonucleoside Biosynthetic Process, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagie, Cancer Immune Checkpoints