TRAIL Antikörper

Produktnummer ABIN7539279

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TRAIL in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für TRAIL Antikörper (ABIN7539279)

Target: TRAIL (TNFSF10) (Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRAIL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TRAIL Antikörper

Verwendungszweck: TRAIL/Apo2L antibody

Spezifität: Chromosomal location:3q26

Aufreinigung: Protein-A purified

Immunogen: recombinant human TRAIL/ApoL2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.

Buffer: PBS

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.

Haltbarkeit: 24 months

Details zu TRAIL

Target: TRAIL (TNFSF10) (Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10))

Andere Bezeichnung: TRAIL/Apo2L

Hintergrund: TNFSF10, TL2, APO2L, CD253, TRAIL, Apo-2L,TNF-related apoptosis-inducing ligand (TRAIL) is a ligand molecule which induces apoptosis. It is a type II transmembrane protein with homology to other members of the tumor necrosis factor family. In humans, the gene that encodes for TRAIL is located at chromosome 3q26. TRAIL binds to the death receptors, DR4 and DR5. The process of apoptosis is caspase-8-dependent. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues.

Gen-ID: 8743

NCBI Accession: NM_003810, NP_003801

UniProt: P50591

Pathways: Apoptose, Positive Regulation of Endopeptidase Activity