IFNA Antikörper (AA 101-189)

Produktnummer ABIN721810

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch IFNA in WB, ELISA, IHC (fro), IF (cc), IF (p) und IHC (p). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für IFNA Antikörper (AA 101-189) (ABIN721810)

Target: IFNA (Interferon alpha (IFNA))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IFNA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-IFNA Antikörper

Bindungsspezifität: AA 101-189

Spezifität: This antibody will detect all 13 subtypes of Human IFN-Alpha

Homologie: Human

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IFNA1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu IFNA

Target: IFNA (Interferon alpha (IFNA))

Andere Bezeichnung: IFN-Alpha

Hintergrund:

Synonyms: IFNA, IFN-a, IFN-_, Interferon alpha, Interferon-alpha, IFNA1, IFNA13, IFNA1/13, IFNA4: IFNA5, IFNA6, IFNA17, IFNA21, IFNA8, IFNA2, IFNA7, IFNA14, IFNA10, IFNA16, Pan Interferon alpha

Background: Interferon-_ (IFN-_, also known as IFN-alpha, IFN-a, IFNA and Interferon-alpha) is a type I interferon and exists as 13 subtypes: IFN-_ 1, 2, 4, 5, 6, 7, 8, 10, 13, 14, 16, 17 and 21. They are mainly produced by virus-infected cells after sensing the presence of danger signals such as viral DNA or RNA. The binding of IFN-_ to its receptor initiates an anti-viral response, but also anti-tumor effects have been shown. A key producer of type I interferons is the plasmacytoid dendritic cell.

Gen-ID: 3439

UniProt: P01562

Pathways: JAK-STAT Signalweg, TLR Signalweg, Hepatitis C, Inflammasome