NEIL1 Antikörper

Produktnummer ABIN7468300

Der Kaninchen Polyklonal Anti-NEIL1 Antikörper wurde für WB validiert. Er ist geeignet, NEIL1 in Proben von Human zu detektieren.

Kurzübersicht für NEIL1 Antikörper (ABIN7468300)

Target: NEIL1 (Endonuclease VIII-Like 1 (NEIL1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NEIL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-NEIL1 Antikörper

Kreuzreaktivität: Human

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human NEIL1. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: 293T , 293T nuclear extract , NEIL1-transfected 293T Validation: Orthogonal, Overexpression

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu NEIL1

Target: NEIL1 (Endonuclease VIII-Like 1 (NEIL1))

Andere Bezeichnung: nei like DNA glycosylase 1

Hintergrund:

Synonyms: nei like DNA glycosylase 1 , FPG1 , NEI1 , hFPG1

Background: NEIL1 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226]).[supplied by OMIM]

Molekulargewicht: 44 kDa

Gen-ID: 79661

UniProt: Q96FI4

Pathways: DNA Reparatur