Calnexin Antikörper

Produktnummer ABIN7468093

Der Maus Monoklonal Anti-Calnexin-Antikörper wurde für WB, IF, IP, ICC und DB validiert. Er ist geeignet, Calnexin in Proben von Human zu detektieren.

Kurzübersicht für Calnexin Antikörper (ABIN7468093)

Target: Calnexin (CANX)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Calnexin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC), Dot Blot (DB)

Güteklasse: KO Validated

Klon: GT1563

Produktdetails anti-Calnexin Antikörper

Spezifität: IP/MS validation was supported by references (PMID:30377428)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Affinity purified by Protein G.

Immunogen: Recombinant protein encompassing a sequence within the center region of human Calnexin. The exact sequence is proprietary.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:10000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: mouse liver , PC-12 , Rat-2 , 293T , A431 , HeLa , HepG2 Validation: IP/MS, KO/KD, Overexpression

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, No Preservative

Konservierungsmittel: Without preservative

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu Calnexin

Target: Calnexin (CANX)

Andere Bezeichnung: calnexin

Hintergrund:

Synonyms: calnexin , CNX , IP90 , P90

Background: This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq]

Molekulargewicht: 68 kDa

Gen-ID: 821

UniProt: P27824

Pathways: MAPK Signalweg, Thyroid Hormone Synthesis