PCNA Antikörper

Produktnummer ABIN7467900

Dieses Maus Monoklonal-Antikörper erkennt spezifisch PCNA in WB, ELISA, IF und ICC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für PCNA Antikörper (ABIN7467900)

Target: PCNA (Proliferating Cell Nuclear Antigen (PCNA))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PCNA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Klon: 339

Produktdetails anti-PCNA Antikörper

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Protein G purified

Immunogen: Recombinant PCNA interdomain connector loop protein

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:1000. ICC/IF: 1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, No Preservative

Konservierungsmittel: Without preservative

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu PCNA

Target: PCNA (Proliferating Cell Nuclear Antigen (PCNA))

Andere Bezeichnung: proliferating cell nuclear antigen

Hintergrund: Proliferating cell nuclear antigen , ATLD2,The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008]

Molekulargewicht: 29 kDa

Gen-ID: 5111

UniProt: P12004

Pathways: Telomere Maintenance, DNA Reparatur, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Autophagie