PKM2 Antikörper (AA 1-50)
Kurzübersicht für PKM2 Antikörper (AA 1-50) (ABIN7454938)
Target
Alle PKM2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-50
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Verwendungszweck
- Rabbit anti-PKM2 Antibody, Affinity Purified
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Homologie
- Orangutan
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Aufreinigung
- Affinity Purified
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Immunogen
- Between AA 1 and 50
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Isotyp
- IgG
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anti-Pyruvate Kinase M2 (PKM2) (AA 294-470) antibody
PKM2 Reaktivität: Human WB, IHC, FACS, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Pyruvate Kinase M2 (PKM2) (AA 141-248) antibodyPKM2 Reaktivität: Human WB, IHC, FACS, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Pyruvate Kinase M2 (PKM2) (AA 476-505), (C-Term) antibodyPKM2 Reaktivität: Human, Maus, Ratte, Affe WB, IHC (p), IF Wirt: Kaninchen Polyclonal RB3697 unconjugated
anti-Pyruvate Kinase M2 (PKM2) (pTyr105) antibodyPKM2 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Pyruvate Kinase M2 (PKM2) (AA 383-417), (C-Term) antibodyPKM2 Reaktivität: Human WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB18405 unconjugated
anti-Pyruvate Kinase M2 (PKM2) (AA 116-145) antibodyPKM2 Reaktivität: Human WB, IHC, FACS, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Pyruvate Kinase M2 (PKM2) (AA 476-505) antibodyPKM2 Reaktivität: Human, Maus, Ratte, Primate WB, IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Pyruvate Kinase M2 (PKM2) (AA 255-350) antibodyPKM2 Reaktivität: Human, Maus, Ratte WB, FACS, ELISA, IHC (p), ICC, IF (p), IF (cc), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Pyruvate Kinase M2 (PKM2) (AA 116-145), (N-Term) antibodyPKM2 Reaktivität: Human WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB15338 unconjugated
anti-Pyruvate Kinase M2 (PKM2) (AA 121-151), (N-Term) antibodyPKM2 Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal RB5870 unconjugated
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Applikationshinweise
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- PKM2 (Pyruvate Kinase M2 (PKM2))
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Andere Bezeichnung
- PKM2
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Hintergrund
- Background: Pyruvate Kinase M2 (PKM2) is a glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. The ratio between the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival. PKM2 also stimulates POU5F1-mediated transcriptional activation, and plays a general role in caspase independent cell death of tumor cells [taken from the Universal Protein Resource (UniProt) P14618].
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Gen-ID
- 5315
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NCBI Accession
- NP_002645
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UniProt
- P14618
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Pathways
- Warburg Effekt
Target
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