SIN3A Antikörper (AA 1-50)

Produktnummer ABIN7453786

Produktdetails anti-SIN3A Antikörper

Target: SIN3A (SIN3 homolog A, transcription regulator (SIN3A))

Bindungsspezifität: AA 1-50

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SIN3A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Verwendungszweck: Rabbit anti-Sin3A Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: between AA 1 and 50

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu SIN3A

Target: SIN3A (SIN3 homolog A, transcription regulator (SIN3A))

Andere Bezeichnung: Sin3A (SIN3A Produkte)

Hintergrund: Background: Sin3A is a part of a histone deacetylase co-repressor complex that functions to stabilize complex members and regulate gene expression through deacetylation of histones. Sin3A acts as a scaffold for a core complex which contains HDAC1, HDAC2, RbAp46, RbAp48, SAP30, RBP1 and p33INHib. Sin3A also associates with the Mad/Max complex to mediate transcriptional repression.

Gen-ID: 25942

NCBI Accession: NP_056292

UniProt: Q96ST3

Pathways: Activation of Innate immune Response, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha