Aktivieren Sie Javascript in Ihrem Browser, um unsere Webseite optimal zu nutzen.

CHEK1 Antikörper (AA 250-300)

Name: CHEK1 Antikörper (AA 250-300)
Brand: antibodies-online
SKU: ABIN7453553
Price: 635.17 EUR
Availability: InStock

Der Kaninchen Polyklonal Anti-CHEK1-Antikörper wurde für WB, IP und IHC (fp) validiert. Er ist geeignet, CHEK1 in Proben von Human zu detektieren.

Produktnummer ABIN7453553

Kurzübersicht für CHEK1 Antikörper (AA 250-300) (ABIN7453553)

Target

Alle CHEK1 Antikörper anzeigen

CHEK1 (Checkpoint Kinase 1 (CHEK1))

Reaktivität

Human

Wirt

Kaninchen

Klonalität

Polyklonal

Konjugat

Dieser CHEK1 Antikörper ist unkonjugiert

Applikation

Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Discover our top product CHEK1 Primärantikörper

Bindungsspezifität
36

28

19

16

9

7

6

5

5

4

3

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 250-300

Verwendungszweck

Rabbit anti-Chk1 Antibody, Affinity Purified

Aufreinigung

Affinity Purified

Immunogen

between AA 250 and 300

Isotyp

IgG
anti-Checkpoint Kinase 1 (CHEK1) (pSer317) antibody
CHEK1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Checkpoint Kinase 1 (CHEK1) (pSer301) antibody
CHEK1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Checkpoint Kinase 1 (CHEK1) (pSer296) antibody
CHEK1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Checkpoint Kinase 1 (CHEK1) (pSer286) antibody
CHEK1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Checkpoint Kinase 1 (CHEK1) (pSer345) antibody
CHEK1 Reaktivität: Human WB, IF, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Checkpoint Kinase 1 (CHEK1) (Middle Region) antibody
CHEK1 Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Pferd, Meerschweinchen WB, IHC Wirt: Kaninchen Polyclonal unconjugated

anti-Checkpoint Kinase 1 (CHEK1) (pSer317) antibody
CHEK1 Reaktivität: Human WB, IHC (p), DB Wirt: Kaninchen Polyclonal RB7845-RB18425 unconjugated

anti-Checkpoint Kinase 1 (CHEK1) (pSer317) antibody
CHEK1 Reaktivität: Maus, Huhn ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

anti-Checkpoint Kinase 1 (CHEK1) antibody
CHEK1 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Monoclonal 2F2 unconjugated Recombinant Antibody

anti-Checkpoint Kinase 1 (CHEK1) antibody
CHEK1 Reaktivität: Human, Maus WB, ELISA Wirt: Maus Monoclonal 2G1D5 unconjugated

Applikationshinweise

IHC: 1:1,000 - 1:5,000. Epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: 1:1,000 - 1:5,000

Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

1000 μg/mL

Buffer

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C

Haltbarkeit

12 months
Target

CHEK1 (Checkpoint Kinase 1 (CHEK1))

Andere Bezeichnung

Chk1

Hintergrund

Background: Chk1 functions as a checkpoint protein kinase that is critical to the regulation of the Cdc25a and Cdc25c phosphatases that promote S and G2/M phase progression, respectively. Chk1 kinase activity inhibits cell cycle progression in the presence of DNA damage by phosphorylating Cdc25a and Cdc25c and causing the degradation of Cdc25a and cytoplasmic sequestration of Cdc25c.

Gen-ID

1111

NCBI Accession

NP_001265

UniProt

O14757

Pathways

p53 Signalweg, Apoptose, Zellzyklus, DNA Reparatur