CAND1 Antikörper (AA 1180-1230)
Kurzübersicht für CAND1 Antikörper (AA 1180-1230) (ABIN7453479)
Target
Alle CAND1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1180-1230
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Verwendungszweck
- Rabbit anti-CAND1 Antibody, Affinity Purified
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Homologie
- Rat,Bovine,Orangutan
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 1180 and 1230
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Isotyp
- IgG
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anti-Cullin-Associated and Neddylation-Dissociated 1 (CAND1) (AA 1-100) antibody
CAND1 Reaktivität: Human WB, ELISA, IF, IHC (p) Wirt: Maus Monoclonal 5D7 unconjugated
anti-Cullin-Associated and Neddylation-Dissociated 1 (CAND1) (AA 1-100) antibodyCAND1 Reaktivität: Human WB, ELISA, IF Wirt: Maus Monoclonal 4D10 unconjugated
anti-Cullin-Associated and Neddylation-Dissociated 1 (CAND1) (AA 1-100) antibodyCAND1 Reaktivität: Human WB, ELISA Wirt: Maus Polyclonal unconjugated
anti-Cullin-Associated and Neddylation-Dissociated 1 (CAND1) (AA 750-980) antibodyCAND1 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Cullin-Associated and Neddylation-Dissociated 1 (CAND1) (AA 1-100) antibodyCAND1 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 5F2 unconjugated
anti-Cullin-Associated and Neddylation-Dissociated 1 (CAND1) (AA 1150-1230) antibodyCAND1 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Cullin-Associated and Neddylation-Dissociated 1 (CAND1) antibodyCAND1 Reaktivität: Human, Maus, Ratte IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Cullin-Associated and Neddylation-Dissociated 1 (CAND1) (C-Term) antibodyCAND1 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio), Fledermaus, Hamster, Affe, Schwein WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Cullin-Associated and Neddylation-Dissociated 1 (CAND1) (AA 1180-1230) antibodyCAND1 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Huhn WB, IHC, IF, IP, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Cullin-Associated and Neddylation-Dissociated 1 (CAND1) (AA 112-161) antibodyCAND1 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio), Fledermaus, Huhn, Hamster, Affe, Schwein, Xenopus laevis WB Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
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IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- CAND1 (Cullin-Associated and Neddylation-Dissociated 1 (CAND1))
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Andere Bezeichnung
- CAND1
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Hintergrund
- Background: Cullin-associated NEDD8-dissociated protein 1 (CAND1) is a regulatory protein that interferes with the assembly of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex and thereby down-regulates ubiquitination of target proteins. CAND1 prevents neddylation of CUL1 by physically blocking access to the neddylation site and disrupts interactions between CUL1 and SKP1A and between CUL1 and F-box proteins. CAND1 also binds TATA binding protein and enhances transcription from various promoters [taken from the Universal Protein Resource (UniProt) Q86VP6].
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Gen-ID
- 55832
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NCBI Accession
- NP_060918
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UniProt
- Q86VP6
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Pathways
- Regulation of Actin Filament Polymerization
Target
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