CAND1 Antikörper (AA 1150-1230)

Produktnummer ABIN7148764

Produktdetails anti-CAND1 Antikörper

Target: CAND1 (Cullin-Associated and Neddylation-Dissociated 1 (CAND1))

Bindungsspezifität: AA 1150-1230

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CAND1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Cullin-associated NEDD8-dissociated protein 1 protein (1150-1230AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CAND1

Target: CAND1 (Cullin-Associated and Neddylation-Dissociated 1 (CAND1))

Andere Bezeichnung: CAND1 (CAND1 Produkte)

Synonyme: TIP120 antikoerper, TIP120A antikoerper, ATCAND1 antikoerper, CULLIN-ASSOCIATED AND NEDDYLATION DISSOCIATED 1 antikoerper, ETA2 antikoerper, HEMIVENATA antikoerper, HVE antikoerper, T8K22.14 antikoerper, T8K22_14 antikoerper, cullin-associated and neddylation dissociated antikoerper, Tip120 antikoerper, Tip120A antikoerper, fb78a05 antikoerper, wu:fb78a05 antikoerper, zgc:55729 antikoerper, tip120 antikoerper, tip120a antikoerper, cand2 antikoerper, 2310038O07Rik antikoerper, 6330512O03Rik antikoerper, AI195005 antikoerper, AI846556 antikoerper, D10Ertd516e antikoerper, Tp120a antikoerper, mKIAA0829 antikoerper, cullin associated and neddylation dissociated 1 antikoerper, cullin-associated and neddylation dissociated antikoerper, cullin-associated and neddylation-dissociated 1 antikoerper, cullin-associated and neddylation-dissociated 1 L homeolog antikoerper, cullin-associated NEDD8-dissociated protein 1 antikoerper, cullin associated and neddylation disassociated 1 antikoerper, CAND1 antikoerper, Cand1 antikoerper, cand1 antikoerper, cand1.L antikoerper, LOC100159824 antikoerper, LOC100177977 antikoerper

Hintergrund:

Background: Key assembly factor of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes that promotes the exchange of the substrate-recognition F-box subunit in SCF complexes, thereby playing a key role in the cellular repertoire of SCF complexes. Acts as a F-box protein exchange factor. The exchange activity of CAND1 is coupled with cycles of neddylation conjugation: in the deneddylated state, cullin-binding CAND1 binds CUL1-RBX1, increasing dissociation of the SCF complex and promoting exchange of the F-box protein. Probably plays a similar role in other cullin-RING E3 ubiquitin ligase complexes.

Aliases: CAND 1 antibody, Cand1 antibody, CAND1_HUMAN antibody, Cullin associated and neddylation dissociated 1 antibody, Cullin associated and neddylation dissociated protein 1 antibody, Cullin associated NEDD8 dissociated protein 1 antibody, Cullin-associated and neddylation-dissociated protein 1 antibody, Cullin-associated NEDD8-dissociated protein 1 antibody, DKFZP434M1414 antibody, FLJ10114 antibody, FLJ10929 antibody, FLJ38691 antibody, FLJ90441 antibody, KIAA0829 antibody, p120 CAND1 antibody, TATA binding protein interacting protein 120A antibody, TBP interacting protein antibody, TBP interacting protein of 120 kDa A antibody, TBP Interacting Protein TIP120A antibody, TBP-interacting protein 120A antibody, TBP-interacting protein of 120 kDa A antibody, TIP120 antibody, TIP120 protein antibody, TIP120A antibody

UniProt: Q86VP6

Pathways: Regulation of Actin Filament Polymerization