Rekombinanter AXL Antikörper (AA 33-440)
Kurzübersicht für Rekombinanter AXL Antikörper (AA 33-440) (ABIN7453376)
Target
Alle AXL Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 33-440
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Verwendungszweck
- Rabbit anti-AXL Recombinant Monoclonal Antibody [BLR222K]
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Immunogen
- residues 33-440(ECD)
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Isotyp
- IgG
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Applikationshinweise
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IP: 6 μL/1 mg lysate
ICC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.
WB: 01:01,00
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- AXL (AXL Receptor tyrosine Kinase (AXL))
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Andere Bezeichnung
- AXL
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Hintergrund
- Background: AXL is a receptor tyrosine kinase (RTK) that binds the ligand Gas6 (growth-arrest specific gene). It is part of a sub-family of RTKs that includes AXL, SKY and MER. The AXL gene was first identified as a transforming cDNA isolated from patients with chronic myelogenous leukemia. AXL-Gas6 signaling is implicated in cellular responses such as cell survival, proliferation, migration, and adhesion, and it may be involved in cancer progression.
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Gen-ID
- 558
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NCBI Accession
- NP_068713
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UniProt
- P30530
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Pathways
- RTK Signalweg, Cellular Response to Molecule of Bacterial Origin
Target
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