Rekombinanter CD25 Antikörper (AA 22-213)
Kurzübersicht für Rekombinanter CD25 Antikörper (AA 22-213) (ABIN7453339)
Target
Alle CD25 (IL2RA) Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 22-213
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Verwendungszweck
- Rabbit anti-CD25/IL-2R alpha Recombinant Monoclonal Antibody [BLR157J]
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Immunogen
- residues 22-213 (ECD)
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Isotyp
- IgG
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anti-Interleukin 2 Receptor, alpha (IL2RA) (AA 34-139) antibody
IL2RA Reaktivität: Human, Maus, Ratte, Affe WB, IHC, ELISA, ICC Wirt: Maus Monoclonal 1B5D12 unconjugated
anti-Interleukin 2 Receptor, alpha (IL2RA) (AA 201-268) antibodyIL2RA Reaktivität: Human, Maus FACS, WB, ELISA, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Interleukin 2 Receptor, alpha (IL2RA) (AA 22-213) antibodyIL2RA Reaktivität: Human WB, ELISA, ICC, IHC (fro), IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Interleukin 2 Receptor, alpha (IL2RA) (AA 34-139) antibodyIL2RA Reaktivität: Human, Maus, Ratte, Affe WB, IHC, ELISA, IF/ICC Wirt: Maus Monoclonal unconjugated
anti-Interleukin 2 Receptor, alpha (IL2RA) antibodyIL2RA Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-181 unconjugated
anti-Interleukin 2 Receptor, alpha (IL2RA) (AA 22-245) antibodyIL2RA Reaktivität: Schwein WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Interleukin 2 Receptor, alpha (IL2RA) antibody (PerCP)IL2RA Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-181 PerCP
anti-Interleukin 2 Receptor, alpha (IL2RA) antibodyIL2RA Reaktivität: Maus, Ratte WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Interleukin 2 Receptor, alpha (IL2RA) (AA 42-183) antibodyIL2RA Reaktivität: Human IHC, StM Wirt: Maus Monoclonal IL2RA-2395 unconjugated
anti-Interleukin 2 Receptor, alpha (IL2RA) (AA 22-235) antibodyIL2RA Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
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IP: 20 μL/1 mg lysate
ICC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.
WB: 01:01,00
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 200 μg/mL
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Buffer
- Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))
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Andere Bezeichnung
- CD25/IL-2R alpha
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Hintergrund
- Background: The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. The IL2 receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells. [taken from NCBI Entrez Gene (Gene ID: 3559)].
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Gen-ID
- 3559
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NCBI Accession
- NP_000408
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UniProt
- P01589
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Pathways
- JAK-STAT Signalweg, Growth Factor Binding, Activated T Cell Proliferation
Target
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