CHEK1 Antikörper (AA 250-300)
Kurzübersicht für CHEK1 Antikörper (AA 250-300) (ABIN7452793)
Target
Alle CHEK1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 250-300
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Verwendungszweck
- Goat anti-Chk1 Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 250 and 300
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Isotyp
- IgG
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Applikationshinweise
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IP: 5 - 20 μg/mg lysate
WB: 1:1,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- CHEK1 (Checkpoint Kinase 1 (CHEK1))
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Andere Bezeichnung
- Chk1
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Hintergrund
- Background: Chk1 functions as a checkpoint protein kinase that is critical to the regulation of the Cdc25a and Cdc25c phosphatases that promote S and G2/M phase progression, respectively. Chk1 kinase activity inhibits cell cycle progression in the presence of DNA damage by phosphorylating Cdc25a and Cdc25c and causing the degradation of Cdc25a and cytoplasmic sequestration of Cdc25c.
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Gen-ID
- 1111
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NCBI Accession
- NP_001265
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UniProt
- O14757
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Pathways
- p53 Signalweg, Apoptose, Zellzyklus, DNA Reparatur
Target
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