CAND1 Antikörper (AA 600-650)
Kurzübersicht für CAND1 Antikörper (AA 600-650) (ABIN7452494)
Target
Alle CAND1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 600-650
-
Verwendungszweck
- Rabbit anti-CAND1 Antibody, Affinity Purified
-
Homologie
- Mouse,Rat,Bovine,Orangutan
-
Aufreinigung
- Affinity Purified
-
Immunogen
- between AA 600 and 650
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
-
IP: 2 - 5 μg/mg lysate
WB: Not recommended
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Konzentration
- 1000 μg/mL
-
Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C
-
Haltbarkeit
- 12 months
-
-
- CAND1 (Cullin-Associated and Neddylation-Dissociated 1 (CAND1))
-
Andere Bezeichnung
- CAND1
-
Hintergrund
- Background: Cullin-associated NEDD8-dissociated protein 1 (CAND1) is a regulatory protein that interferes with the assembly of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex and thereby down-regulates ubiquitination of target proteins. CAND1 prevents neddylation of CUL1 by physically blocking access to the neddylation site and disrupts interactions between CUL1 and SKP1A and between CUL1 and F-box proteins. CAND1 also binds TATA binding protein and enhances transcription from various promoters [taken from the Universal Protein Resource (UniProt) Q86VP6].
-
Gen-ID
- 55832
-
NCBI Accession
- NP_060918
-
UniProt
- Q86VP6
-
Pathways
- Regulation of Actin Filament Polymerization
Target
-