XPC Antikörper (AA 825-875)
Kurzübersicht für XPC Antikörper (AA 825-875) (ABIN7452477)
Target
Alle XPC Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 825-875
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Verwendungszweck
- Rabbit anti-XPC Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 825 and 875
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Isotyp
- IgG
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Applikationshinweise
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IP: 2 - 5 μg/mg lysate
WB: Not recommended. Use rabbit anti-XPC antibody ABIN7452171.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- XPC (Xeroderma Pigmentosum, Complementation Group C (XPC))
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Andere Bezeichnung
- XPC
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Hintergrund
- Background: Defects in XPC are a cause of xeroderma pigmentosum complementation group C, a rare autosomal recessive diseased characterized by hypersensitivity to sunlight and an elevated risk of skin cancer on sun-exposed areas. XPC is involved in nucleotide excision repair and performs its function as part of a heterodimeric complex with HHR23B. XPC has been found to play a role in the early stages of repair that involve incising damaged DNA.
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Gen-ID
- 7508
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NCBI Accession
- NP_004619
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UniProt
- Q01831
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Pathways
- p53 Signalweg, DNA Reparatur
Target
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