TAB2 Antikörper (AA 300-350)
Kurzübersicht für TAB2 Antikörper (AA 300-350) (ABIN7452448)
Target
Alle TAB2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 300-350
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Verwendungszweck
- Rabbit anti-TAB2 Antibody, Affinity Purified
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Homologie
- Mouse,Rat
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 300 and 350
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Isotyp
- IgG
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Applikationshinweise
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IP: 2 - 5 μg/mg lysate
WB: Not recommended. Use rabbit anti-TAB2 antibody ABIN7452084.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- TAB2 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2))
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Andere Bezeichnung
- TAB2
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Hintergrund
- Background: TAB2 (TGF-beta-activated kinase 1and MAP3K7-binding protein 2) functions as an activator of MAP3K7/TAK1, which is required for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. TAB2 forms a kinase complex with TRAF6, MAP3K7 and TAB1, and thus serves as an adaptor linking MAP3K7 and TRAF6. TAB2, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts [taken from NCBI Entrez Gene (GeneID: 23118)].
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Gen-ID
- 23118
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NCBI Accession
- NP_055908
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UniProt
- Q9NYJ8
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Pathways
- T-Zell Rezeptor Signalweg, TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades, Ubiquitin Proteasome Pathway
Target
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