Phospholipase C gamma 1 Antikörper (AA 1240-1290)
Kurzübersicht für Phospholipase C gamma 1 Antikörper (AA 1240-1290) (ABIN7451964)
Target
Alle Phospholipase C gamma 1 (PLCG1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1240-1290
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Verwendungszweck
- Rabbit anti-PLC-gamma 1 Antibody, Affinity Purified
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Homologie
- Rat
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 1240 and 1290
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Isotyp
- IgG
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Applikationshinweise
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IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- Phospholipase C gamma 1 (PLCG1) (phospholipase C, gamma 1 (PLCG1))
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Andere Bezeichnung
- PLC-gamma 1
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Hintergrund
- Background: PLC-gamma1 catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. Also, PLC-gamma1 has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase [taken from NCBI Entrez Gene (Gene ID: 5335].
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Gen-ID
- 5335
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NCBI Accession
- NP_877963
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UniProt
- P19174
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Pathways
- RTK Signalweg, WNT Signalweg, T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Thyroid Hormone Synthesis, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Interaction of EGFR with phospholipase C-gamma, VEGFR1 Specific Signals, VEGF Signaling
Target
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