GLI2 Antikörper (AA 950-1000)

Produktnummer ABIN7451134

This anti-GLI2 antibody (ABIN7451134) is a Rabbit Polyclonal antibody detecting GLI2 in IP. Suitable for Human.

Quick Overview for GLI2 Antikörper (AA 950-1000) (ABIN7451134)

Target: GLI2 (GLI Family Zinc Finger 2 (GLI2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GLI2 Antikörper ist unkonjugiert

Applikation: Immunoprecipitation (IP)

Produktdetails anti-GLI2 Antikörper

Bindungsspezifität: AA 950-1000

Verwendungszweck: Rabbit anti-GLI2 Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: Between AA 950 and 1000

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: 2 - 10 μg/mg lysate

WB: Not recommended. ABIN7451134 has not performed satisfactorily when used for WB of GLI2 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of GLI2.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu GLI2

Target: GLI2 (GLI Family Zinc Finger 2 (GLI2))

Andere Bezeichnung: GLI2

Hintergrund: Background: GLI2 functions as transcription regulator in the hedgehog (Hh) pathway (PubMed:18455992). GLI2 may also function as transcriptional repressor (By similarity). It requires STK36 for full transcriptional activator activity. GLI2 is required for normal embryonic development (PubMed:15994174, PubMed:20685856) [taken from NCBI Entrez Gene (Gene ID: 2736)].

Gen-ID: 2736

UniProt: P10070

Pathways: Hedgehog Signalweg, Dopaminergic Neurogenesis