Telefon:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antikoerper-online.de

GLI2 Antikörper (GLI Family Zinc Finger 2) Internal Region Primary Antibody

GLI2 Reaktivität: Maus IHC, ELISA, WB Wirt: Kaninchen Polyclonal unconjugated
Pubmed (1 reference)
Produktnummer ABIN129624
$658.50
Zzgl. Versandkosten $45.00 und $20.00 Trockeneis
100 μg
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 1 bis 2 Werktagen
  • Target Alle GLI2 Antikörper anzeigen
    GLI2
    Bindungsspezifität
    • 9
    • 7
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    • 48
    • 14
    • 6
    • 2
    • 2
    • 1
    Maus
    Wirt
    • 41
    • 7
    • 2
    Kaninchen
    Klonalität
    • 48
    • 2
    Polyklonal
    Konjugat
    • 20
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Dieser GLI2 Antikörper ist unkonjugiert
    Applikation
    • 24
    • 21
    • 13
    • 6
    • 6
    • 5
    • 1
    • 1
    Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
    Produktmerkmale
    Concentration Definition: by UV absorbance at 280 nm
    Immunogen
    This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids from an of Mouse Gli-2.
    Isotyp
    IgG
  • Applikationshinweise
    This antibody has been tested for use in ELISA, immunohistochemistry and western blot.  Specific conditions for reactivity should be optimized by the end user. See figure legend for expectations by WB and IHC.  Multiple splice variants have been reported for this protein.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1.02 mg/mL
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
  • Guntur, Reinhold, Cuellar, Naski: "Conditional ablation of Pten in osteoprogenitors stimulates FGF signaling." in: Development (Cambridge, England), Vol. 138, Issue 7, pp. 1433-44, (2011) (PubMed).

  • Target
    GLI2
    Andere Bezeichnung
    Gli-2 (GLI2 Produkte)
    Synonyme
    HPE9, THP1, THP2, GLI2/GLI4, GLI3, AW546128, GLI family zinc finger 2, GLI-Kruppel family member GLI2, GLI2, Gli2
    Hintergrund
    Gli-2 (also known as Zinc Finger Protein Gli-2, GLI-Kruppel family member GLI-2 or Tax helper protein) belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors that bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling, and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. Gli-2 is also thought to play a role during embryogenesis. The encoded protein is associated with several phenotypes: Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, pre-axial
    Synonyms: Gli 2 antibody, GLI family zinc finger 2 antibody, GLI kruppel family member 2 antibody, GLI Kruppel family member GLI2 antibody, Oncogene GLI2 antibody, Tax helper protein antibody, Tax helper protein 2 antibody
    Gen-ID
    14633, 124487481
    UniProt
    Q8K0K3
    Pathways
    Hedgehog Signalweg, Dopaminergic Neurogenesis
Sie sind hier:
help Kundenservice